http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2193086-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a717ea5b2ac78ac329ab3a9659d834d2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-724 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-724 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-737 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 1995-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5b1dcb2e44eed69d2c8546c8ca638ae |
| publicationDate | 1995-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2193086-A1 |
| titleOfInvention | Esterified polyanionic cyclodextrins as smooth muscle cell proliferation inhibitors |
| abstract | This invention relates to esterified polysulfated cyclodextrins, their use in treating diseases and conditions which are characterized by excessive smooth muscle cell (SMC) proliferation such as restenosis and a pharmaceutical composition thereof. The compounds useful in this invention are represented by Formula (I), where: M is a pharmaceutically acceptable cation; p is 1 or 2; q is n/2 when p is 2 and q is n when p is 1; R is selected from the group consisting of C1-C12 lower alkyl, C3-C12 cycloalkyl, and aryl or heteroaryl optionally substituted with 1-3 substituents independently selected from halogen, C1-C12 lower alkyl or C1-C12 alkoxy; and n is an integer from 6 - 8, representing .alpha.-cyclodextrin (n = 6), .beta.-cyclodextrin (n = 7), and .gamma.-cyclodextrin (n = 8). |
| priorityDate | 1994-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.