http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2192790-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c11d61eb758111c4e78e8ad81eef2fcd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_600db5b93a54999d3db277d10725d525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56977 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
filingDate | 1995-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c76d8a00bf2f914b8b7364d2f49bc07f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c8f29c136680132de717b9591d59858 |
publicationDate | 1996-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2192790-A1 |
titleOfInvention | Long term xenogeneic myeloid and lymphoid cell production in chimeric immunocompromised animals |
abstract | Immunocompromised mammalian hosts are subcutaneously implanted with a combination of human fetal bone and spleen. The chimeric animals can produce human B-cells, myeloid cells and T-cells for up to 9 months in vivo when supplied with an allogeneic human fetal thymic fragment at the same site. Grafts contain cell populations expressing CD4 and CD8, CD19 or CD33, CD14 and CD15, all of which also express the HLA type of the fetal bone/spleen. T-cells derived from progenitors in the fetal bone/spleen contain both mature single positive CD4+CD8-, CD8+CD4- as well as a high percentage of immature double positive CD4+CD8+ populations. |
priorityDate | 1994-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 133.