http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2192678-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d6efce1f6198d69838bbf9f04900a11 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3069 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
| filingDate | 1995-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62262e55197b2e0833cf178a99a3102b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e715556f9f6036e2f75a16bb367a113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7ca258f664f69ec482d6c463b9b5935 |
| publicationDate | 2010-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2192678-C |
| titleOfInvention | Mn gene and protein |
| abstract | A complete genomic sequence including a full-length cDNA sequence for the MN gene, a putative oncogene, is disclosed, as well as proteins/polypeptides encoded thereby Recombinant nucleic acid molecules for expressing MN proteins/polypeptides and recombinant proteins are also provided. Expression of the MN gene is disclosed as being associated with tumorigenicity, and the invention concerns methods and compositions for detecting and/or quantitating MN antigen and/or MN-specific antibodies in vertebrate samples that are diagnostic/prognostic for neoplastic and preneoplastic disease. Test kits embodying the immunoassays of this invention are provided, MN-specific antibodies are disclosed that can be used diagnostically/prognostically, therapeutically, for imaging, and/or for affinity purification of MN proteins/polypeptides. Also provided are nucleic acid probes for the MN gene as well as test kits comprising said probes The invention also concerns vaccines comprising MN proteins/polypeptides which are effective to immunize a vertebrate against neoplastic diseases associated with the expression of MN proteins. The invention still further concerns antisense nucleic acid sequences that can be used to inhibit MN gene expression, and polymerase chain reaction (PCR) assays to detect genetic rearrangements in MN genes. |
| priorityDate | 1994-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 702.