http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2192459-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a717ea5b2ac78ac329ab3a9659d834d2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
| filingDate | 1995-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d4235d41f6d48e48238c99a82ce4c7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f42f8cff8dae631b19ec8798d63092ee |
| publicationDate | 1995-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2192459-A1 |
| titleOfInvention | 4-carbamoyloxy-piperidine-1-carboxylic acid esters: inhibitors of cholesterol absorption |
| abstract | Compounds which inhibit the enzyme cholesterol ester hydrolase (CEH) thus inhibit the formation of esterified cholesterol. Esterified cholesterol is absorbed through the intestine and inhibition of the enzyme therefore results in inhibition of cholesterol absorption. The compounds of this invention inhibit cholesterol ester hydrolase and have formula (I), wherein Z is -Ar1, -Ar1-Ar2, -Ar1-O-Ar2, -Ar1-S-Ar2, (a), (b), (c), -Ar1-(CH2)1-20-Ar2, -Ar1-(CH2)1-20-O-Ar2, -Ar1-O-(CH2)1-20-Ar2, -Ar1-(CR6=CR6)1-3-Ar2 or -Ar1-NR7-Ar2; and A is a hydrocarbon linking group which may be interrupted by a heteroatom or a cycloalkyl, aryl, heterocycloalkyl, or an azacycloalkyl group; and R4 and R5 are independently alkyl, alkenyl, acyl, alkoxycarbonyl or H or R4 and R5 together with the interposed nitrogen form a saturated heterocyclic ring. |
| priorityDate | 1994-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 140.