http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2191302-A1

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filingDate 1995-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa03edc42f828c64fa42d27ece127084
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publicationDate 1995-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2191302-A1
titleOfInvention Pharmaceutical preparation with a hydrophobic active substance and an effervescent system, and process for preparing said preparation
abstract The invention concerns pharmaceutical effervescent tablets with at least one hydrophobic active substance, such as for example loratadine or cisapride, and a surfactant. These effervescent tablets advantageously contain at least two different surfactants or emulsifiers, in particular from the group comprising sugar esters, polysorbates and phospholipids. At least one of the emulsifiers can be present in the mixture in the form of granules separately from the effervescent system and/or active substance granules. Preferably, the active substance is also precipitated in the form of separate active substance granules - for example by means of a binder, such as for example polyvinylpyrrolidone - on the surface of a suspended substance or anti-adhesive substance, such as for example Aerosil or Avicel. The active substance can, moreover, contain at least one of the effervescent components and/or a filler which preferably comprises at least one of the following compounds: higher alcohols, e.g. mannitol, sorbitol or lactose; hydrocolloids, such as maltodextrin or dextrin; and starch.
priorityDate 1994-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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