| abstract |
Combinatorial libraries are disclosed which are represented by the Formula (I): (T'-L)q- S -C(O)-L'-II' wherein S is a solid support; T'-L- is an identifier residue; and -L'-II' is a ligand/linker residue. These libraries contain dihydrobenzopyrans of formula (II) which interact (i.e., as agonists or antagonists) with .alpha. adrenergic receptors, dopamine receptor, .sigma.opiate receptors, and K+ channels and are inhibitors of carbonic anhydrase isozymes. They are useful in the treatment of ocular diseases such as glaucoma. |