http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2187624-C
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e40ceab05afbe887909abf7467edd987 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-10061 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-746 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-70 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74 |
filingDate | 1995-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2003-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a175625d9615ba393801b1e40ad7f952 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_893d0d64626ce23175f5a46782f28112 |
publicationDate | 2003-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2187624-C |
titleOfInvention | Method of eliminating genetic routes for bacteriophage evolution and products produced thereby |
abstract | -45- The present invention provides a method of identifying a bacterial DNA sequence capable of recombining with DNA of a predetermined bacteriophage the method comprises the steps of: (a) introducing a bacteriophage defense mechanism into a bacterium; (b) culturing the bacterium in the presence of a first lytic bacteriophage to produce a bacterial culture, the first lytic bacteriophage being sensitive to the bacteriophage defense mechanism; (c) isolating from the bacterial culture a second lytic bacteriophage which is resistant to the bacteriophage defense mechanism; (d) identifying DNA sequences present in the second lytic bacteriophage which are not present in the first lytic bacteriophage; and then (e) identifying a bacterial DNA sequence which is homologous to a DNA sequence of the second lytic bacteriophage identified in step (d); wherein the identified bacterial DNA sequence is capable of recombination with DNA of the first lytic bacteriophage. |
priorityDate | 1994-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 186.