http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2186876-A1

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-083
filingDate 1995-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4268e3e8879c3b47daf774d6d5b6856
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b1a02295dc64c16eded5d06c4ce263f
publicationDate 1995-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2186876-A1
titleOfInvention Apparatus for detecting and correcting airflow limitation
abstract Inspiratory flow limitation (IFL) is involved in the pathophysiology of sleep-related breathing disorders. Since the definition of flow-limited cycle is based on a dissociation between flow and respiratory efforts, identification of IFL requires upper airway or intrathoracic pressure measurements. We examined the feasability and accuracy of the analysis of the flow-volume loop of a tidal breath in identifying IFL. The tidal volume was obtained by integration of the instantaneous airflow signal, and the flow-volume loop was reconstructed for each breathing cycle by plotting the instantaneous flow and the tidal volume. The instantaneous inspiratory and expiratory flows were measured at a 50 % of the respective (inspiratory or expiratory) portion of the tidal volume, and a breath-by-breath analysis of the mid tidal volume flow ratio (I/E ratio) was obtained. There was a positive significant relationship between I/E ratio and VImax (maximal inspiratory volume) for flow-limited breathing (correlation coefficient range: 0.25-0.54). With a lower limit of the normal I/E ratio threshold of 0.97, the sensitivity and specificity of the method were both 76 %. Patients having a I/E ratio lower than 0.97 to 1 are classified as suffering IFL. Therefore, the present invention relates to the above-described non-invasive method which is applicable in the evaluation IFL and to an apparatus measuring I/E ratio and correcting IFL.
priorityDate 1994-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 19.