http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2186263-C
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 |
filingDate | 1995-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1999-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_609b5aa90ecba10028b07d737f41b39f |
publicationDate | 1999-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2186263-C |
titleOfInvention | Separation of the enantiomers of amlodipine via their diastereomeric tartrates |
abstract | A method for the separation of R-(+)- and S-(-)-isomers of amlodipine (I) from mixtures thereof, which comprises the reaction of the mixture of isomers with either L- or D-tartaric acid in an organic solvent containing sufficient dimethyl sulphoxide (DMSO) for the precipitation of, respectively, a DMSO solvate of an L-tartrate salt of R-(+)-amlodipine, or a DMSO solvate of a D-tartrate salt of S-(-)-amlodipine. |
priorityDate | 1994-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.