Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20c1daf0f5ffabe6e9803c06e252035e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-43573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0331 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57419 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
1996-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae6b4a2e8e756daed8b214d4beb6fcd1 |
publicationDate |
1998-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2184780-A1 |
titleOfInvention |
Methods of diagnosing and treating cancer |
abstract |
The present invention relates generally to methods of diagnosing and treating cancer and more particularly colon cancer. Even more particularly, the present invention provides a genetically manipulated live animal model useful for developing diagnostic and treatment protocols for colon cancer. The present invention further provides agents useful for diagnosing and treating colon cancer in animals such as mammals including humans. In a particularly preferred embodiment the present invention provides a genetically altered animal or progeny of said animal wherein said animal comprises a mutation in at least one allele of Cdx2 or equivalent thereof and which is a homologue of the Drosophila caudal gene and wherein said genetically altered animal has a predisposition to develop growth of neoplastic cells in intestinal epithelium. |
priorityDate |
1996-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |