abstract |
Novel substituted fluorene compunds of Formula I are active as melatonergic agents: (I) wherein: X= H, halogen, OH or OZ; Z= C1-6 alkyl;-(CH7)m-CF3 (m=0-2); CD3; or (m'=1-3); n=1 or 2; and R= C1-6 alkyl, C3-6 cycloalkyl, C2-4 alkenyl, halogen substituted C1-6 alkyl, or C1-6 alkoxy substituted C1-6 alkyl. |