http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2176370-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5fe74855697fef20a2e98a9b005db19 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-575 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 |
| filingDate | 1994-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ba7377b5cf6ab053a38c9e78712f2d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52851073de7a23c4a2a2f1bc744ddc40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d31de1f95ae61708aca38616f1389ae1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3716c8a09a8e43f851c19822609ed0c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8cc17f9822002ee2236f52d8ec6e8ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ff9e5054e353fad461ad22a00fc5861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7abc6c6c89a1db07978190727ce67ab5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f136013a8d94f60041a2bf3a43e8a892 |
| publicationDate | 1995-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2176370-A1 |
| titleOfInvention | The Use of Steroids Having a Phenolic A-Ring Structure for Prophylaxis and Therapy of Radical-Mediated Cellular Trauma |
| abstract | The present invention pertains to new pharmaceutical preparations for prophylaxis and therapy of radical-mediated cell damage, consisting of steroids with phenolic A-ring structure-except the esterogens estradiol, estrone, estrione and their 2-hydroxy derivates as well as the steroids with cyclic substituents or with am amino group at the terminal C atom of the aliphatic C-17 side chain-and of pharmaceutical adjuvants. These preparations are characterized by a high-level inhibiting action against cell and tissue changes, such as lipid peroxidation and the oxidation of low density lipoprotein (LPL) cholesterol, caused by reactive oxygen species (ROS), free oxygen radicals and other forms of radical; these preparations thus prevent irreversible membrane and endothelial damage resulting therefrom. They therefore contribute to improving the prophylaxis and therapy of radical-induced damage such as that caused by oxygen radicals and/or ROS. |
| priorityDate | 1993-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.