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filingDate 1994-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2000-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d95da9caf29507fdda51f1493f1e71b
publicationDate 2000-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2175451-C
titleOfInvention Isolated components of dense microspheres derived from mammalian brain tissue and antibodies thereto
abstract Dense microspheres (DMS) present in the brain of individuals susceptible to cerebral amyloidosis disintegrate into DMS components to form cerebral amyloid plaques and other DMS components that are removed from the brain via circulating bodily fluids. Detecting the presence of these removed DMS components in circulating bodily fluids provides a diagnostic mechanism to determine the onset of cerebral amyloid plaque formation. Antibodies also can be raised against isolated DMS components and subsequently utilized in a diagnostic method capable of detecting the onset of cerebral amyloid plaque formation.
priorityDate 1993-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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