http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2175370-C

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82b460ae2c0d553a2db7abd984e85631
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
filingDate 1994-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2006-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19e68c1299bbdae69ff755f8fe43b5b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e898b71e9c3c2d02a3f600633ccca198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7af7324f51ff744c8fb14723259e2358
publicationDate 2006-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2175370-C
titleOfInvention Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
abstract A pharmaceutical composition comprising biodegradable and biocompatible microparticle containing a 1,2-benzazole of the formula (I), or a pharmaceutically acceptable acid addition salt thereof, wherein R is hydroge n or C1-6alkyl; R1 and R2 independently are hydrogen, halo, hydroxy, C1- 6alkyloxy and C1-6alkyl; X is O or S; Alk is C1-4alkanediyl; and R3 is hydrogen or C1-6alkyl; Z is -S-, -CH2, or -CR4=CR5-; where R4 and R5 independently are hydrogen or C1-6alkyl; A is a bivalent radical -CH2-CH2-, - CH2-CH2-CH2- or -CR6=CR7-; wherein R6 and R7 are hydrogen, halo, amino or C1 - 6alkyl; and R8 is hydrogen or hydroxyl; within a polymeric matrix.
priorityDate 1993-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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