http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2171057-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9fa13c33b79ba86e25d61d5e3cee4f2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-336 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-336 |
| filingDate | 1996-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba24bfd6d4b960b372d404209054d85e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afcea10724ed4b519f1530acffbdda11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ef6fc7b310e4a755cf2e016fc64c2eb |
| publicationDate | 1996-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2171057-A1 |
| titleOfInvention | Corneal opacification inhibitory composition |
| abstract | An ophthalmic preparation which comprises a fumagillol derivative represented by the general formula(I): (I) wherein R1 is hydrogen; R2 is a halogen, N(O)mR5R6, N+R5R6R7 X-, S(O)nR5 or S+R5R6 X-, wherein R5, R6 and R7 represent independently a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group; X- represents a counter anion; m represents 0 or 1; n represents an integer from 0 to 2; or R5 and R6 together with the adjacent nitrogen or sulfur atom may form a substituted or unsubstituted nitrogen- or sulfur-containing heterocyclic group which may form a condensed ring ; or R1 and R2 are combined to represent a chemical bond; R3 is a substituted or unsubstituted 2-methyl-1-propenyl group or a substituted or unsubstituted isobutyl group; A is oxygen or NR8, wherein R8 represents hydrogen, a substituted or unsubstituted lower alkyl group or a substituted or unsubstituted aryl group ; and R4 is hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted acyl group and a salt thereof is useful for inhibiting corneal opacification occurring after ophthalmic surgery. |
| priorityDate | 1995-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.