| abstract |
Ortho-substituted benzoic acid derivatives of the formula I I, in which R1, R2 and R3 have the given meanings, and Q is guanidyl, and also their physiologically harmless salts, exhibit antiarrhythmic properties and act as inhibitors of the cellular Na+/H+ antiporter. In addition, the compounds of the formula I, in which R1 to R3 and also Q have the given meanings, are suitable for use as valuable intermediates for the preparation of medicaments, in particular of inhibitors of the cellular Na+/H+ antiporter. |