| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ad66884a6f2a66126d492e56e09be39 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 |
| filingDate |
1994-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d4e46c47a9c109a4475b6ad5cd2d00d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9af08daed6f9c97341ff1843eedb825d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_299f86774999429ffba0bcb347f405f8 |
| publicationDate |
2004-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2153893-C |
| titleOfInvention |
The preparation of colloidal aqueous solutions of active substances of low solubility and a lipid therefor |
| abstract |
A method for forming a solution of only slightly soluble active substances is described, comprising the following steps: a) the active substance is dissolved, together with a phospholipid and a water-soluble lipid, in an organic solvent; 2) the solution thus obtained is reduced in volume; 3) die residue is taken up in a strongly acid buffer solution and stirred at elevated temperature until a colloidal solution forms; 4) the colloidal solution is cooled its pH adjusted to a value of 6 to 7 and the solution sterilized. Particularly suitable for use in this method are lipids of formula (I) In which m, a, b, z and y are as defined in the description. |
| priorityDate |
1993-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |