http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2149731-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7522a25ec96a1ded63bdbd25129cb165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3c9f9bab0ee858ab3414f19674a7eaef |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-26 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-26 |
filingDate | 1995-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1d62f35f1d64f6248dd0b34c95aefb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25d0b08a5d817fab61bb84ef31a334f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b2ac8c1dbd93cd4931e46c465017606 |
publicationDate | 1995-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2149731-A1 |
titleOfInvention | Specialized antibody treatment for brain neoplasm |
abstract | A method of treating malignant brain cells, and pharmaceutical composition therefor, by transporting or injecting into the area of those cells at least one monoclonal antibody which specifically reacts with an epitope present on the carboxy-terminal peptide of the beta (.beta.) subunit of human chorionic gonadotropin. The antibody(ies) may be carried across the blood-brain barrier by stereotactic injection, or may be administered intraarterially (intracarotid administration, for example) in conjunction with an osmotic agent which allows at least some of the monoclonal antibody(ies) to pass the blood-brain barrier. Three examples of this class of monoclonal antibodies--CTP101, CTP102 and CTP103--have been administered in an established animal model to show efficacy of treatment of human brain cancer. |
priorityDate | 1994-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.