| abstract |
Method of treating 5-HT3-mediated disorders, which comprises systemic administration of an effective amount of a compound of formula (I), the pharmaceutically acceptable acid addition salt forms and the stereochemically isomeric forms thereof, wherein R1 and R2 represent hydrogen or R1 and R2 taken together form a bivalent radical of formula (a): -CH = CH-CH = CH-, (b): -CH = C(C1)CH = CH- or (c): -CH = CH-C(C1) = CH-: n represents 2, 3 or 4; R3 represents hydrogen or methoxy; m represents 1 or 2; R4 represents hydrogen, amino or C1-3-alkylcarbonylamino; and R5 represents hydrogen or halo; novel compounds; compositions; processes for preparing novel compounds and intermediates. |