Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e06d8df5ecb58e082a70a2bd8c474836 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
1995-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e058780810db18b80bc29c40786f320b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08fa66a927aa587ab2f0a4deadce745b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2d6be8ca905b7d8b7133a03f920800a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86726c6405bec005ba2fbc314d195f1a |
publicationDate |
1995-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2145623-A1 |
titleOfInvention |
Modulatory proteins of human cns receptors |
abstract |
ABSTRACT Neurotransmission by excitatory amino acids (EAAs) such as glutamate is mediated via membrane-bound surface receptors. This neurotransmission has been found to be modulated by certain modulatory proteins. DNA coding for a family ofsuch modulatory proteins has now been isolated and the modulatory proteins have been characterized. Herein described are recombinant cell lines which produce these modulatory proteins as heterologous membrane-bound products. Also described are related aspects of the invention, which are of commercial significance, including the use of cell lines which express the modulatory proteins either homomerically, orheteromerically in a complex with an NMDA receptor, as a tool for discovery of compounds which affect the function of the modulatory proteins. |
priorityDate |
1994-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |