http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2141475-C
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate | 1995-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1999-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b957d81b3e93d87c8d1208925f686212 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1ecab7200f40812fef9e6fea2726e01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4079546e72c689720cf23497be549c7 |
publicationDate | 1999-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2141475-C |
titleOfInvention | Type 1 and type p fimbriae-adhesins isolated from novel e. coli strains, process for their preparation and uses thereof |
abstract | Fimbriae adhesins have a molecular weight of 2x10 5 and 2x10 7 Da, and comprise 90-95% protein and 1-3% sugar. Type 1 fimbriae show 5 different protein fractions of 14-20 kDa, most of which are associated to carbohydates. Type P fimbriae also include 5 different protein fractions of 14-20 kDa, one of the majority ones being associated to carbohydrates. The process comprises: culturing E. coli strains CECT 4484 and CECT 4485; collecting the sediment by centrifugation, resuspending it in physiological saline and homogenizing it; centrifuging the homogenate collecting the supernatant, which is subjected to saline precipitation, reconstituting the precipitate and dialyzing the solution; treating the dialyzate with sodium deoxcholate and, subjecting the product to two successive chromatographies with Sephacryl S-200 and Sepharose 4B. Use in treating and preventing infections of the urinary tract produced by fimbriated E. coli. |
priorityDate | 1994-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 296.