Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d31d7e10aeb9b0303f5b5e5139f5a64c |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-727 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-715 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-727 |
filingDate |
1993-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2003-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ff49faa4839f4b9b532daafb0167673 |
publicationDate |
2003-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2140890-C |
titleOfInvention |
Medicament for inhibiting neutrophil elastase and cathepsin g |
abstract |
A method and medicament for the inhibition of neutrophil elastase and cathepsin G in mammals comprising administer-ing a treatment effective amount of 2-O-desulfated heparin to a mammal in need thereof. The medicament preferably is adminis-tered by aerosolization or by intravenous (IV) injection. In specific embodiments of the invention, the ratio of 2-O-desulfated he-parin to elastase is greater than about 0.2 and less than about 2.0, or the ratio of 2-O-desulfated heparin to cathepsin G is greater than about 0.4 and less than about 2Ø Preferably, the 2-O-desulfated heparin medicament includes a physiologically acceptable carrier which may be selected from the group consisting of physiologically buffered saline, normal saline, and distilled water. |
priorityDate |
1992-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |