http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2140293-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db8acd71f5994544bda6df3f27a3f51e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22 |
| filingDate | 1993-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ba8828fe733efa7e3eca7507305e25d |
| publicationDate | 1994-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2140293-A1 |
| titleOfInvention | Radioimaging and radiochemotherapy phenolic thioether amines and acyl derivatives thereof for use in diagnosing and treating pigmentation disorders |
| abstract | Hydroxyphenylthioalkyl amines represented by formula (I), wherein R1 is H or C1-C8 alkyl; R2 is H or C1-C8 alkyl; R3 is H, C1-C8 alkyl or C1-C8 alkanoyl; R4 is H or C1-C8 alkanoyl; Ra is a radioactive material useful in radioimaging and/or radiochemotherapy where the dottet line (---) indicates: 1) Ra is covalently bound to the structure of formula (I); 2) Ra is ionically associated with the structure of formula (I); 3) Ra is radioactive carbon which is part of the structure of formula (I); and x is 1 to 5, with the provisos that when x is 1, one of R1, R2 or R3 is other than H, and that the sulphur containing group and the Ra group are in the 2, 4 or 6 positions of the phenyl ring, are useful in radioimaging and radiotherapy. Preferred compounds for use in radioimaging are N-acetyl-4-S-cysteaminylphenol and N-¢2-¢(4'-acetoxyphenyl)thio!ethyl!acet-amide. The O-acylated derivatives are novel and are also useful in treatment of pigment disorders. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113777191-A |
| priorityDate | 1992-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.