abstract |
Invented are 17.alpha. and 17.beta.-alkylketone-3-carboxy aromatic A ring analogues of steroidal synthetic compounds, pharma-ceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5-.alpha.-reductase iso-zyme 1 and steroid 5-.alpha.-reductase isozyme 2. Also invented are intermediates and processes used in preparing these compounds. |