http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2138932-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce3ceb49a54edfbc6b35e9109347c463 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y599-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-90 |
| filingDate | 1994-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b03d72029121d8f6eba7214e3f15503 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e43cbb96cf920e445a1bb8a7a13b4541 |
| publicationDate | 1995-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2138932-A1 |
| titleOfInvention | Mutant proteins of human dna topoisomerase i |
| abstract | Mutant proteins of human DNA topoisomerase I having an amino acid sequence in which tyrosine at the 592nd position of human DNA topoisomerase I is lacking or replaced with phenylala-nine and which contains at least 30 amino acids in succession of the amino acid sequence subsequent to the 542nd amino acid of human DNA topoisomerase I. Above described mutant proteins react with anti-Scl-70, antibody in the sera of autoimmune disease patients of diffuse scleroderma and can be produced by genetic engineering using E. coli, and therefore they are useful as a diagnostic reagent for scleroderma. |
| priorityDate | 1993-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 417.