| abstract |
2136211 9323389 New taxane derivatives of general formula (I), their preparation and the pharmaceutical compositions containing them. In the general formula (I), Ar represents an aryl radical, R1 represents a hydrogen atom or an acetyl radical or a radical of formula (II) (R1 and R2 represent hydrogen, alkyl or together form a heterocycle, n is 2 or 3); R represents alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl or heterocyclyl. New products from general formula (I) have anti-tumor activity remarkable. |