| abstract |
An indole derivative represented by formula (1), wherein A is a group wherein R10 is hydrogen or lower alkyl, dotted lines may optionally be present, and R1-R9 represents various substitutional groups. The compound. (1) exhibits a positive inotropic action on cardiac muscle, an anti-arrhythmic action, and a vasodilation action without increasing the heart rate. A heart affection therapeutic agent comprising this compound as an effective component is extremely effective for treating heart failures and arrhythmia. |