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filingDate 1994-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc10893a7f63b8462deed337d1c705eb
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publicationDate 1995-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2126911-A1
titleOfInvention Isolation and structure of spongistatin 2, spongistatin 3, spongistatin 4 and spongistatin 6
abstract A black Spongia sp, in the Porifera class Demospongiae has been found to contain two new and exceptionally active cell (human cancers growth inhibitors,named spongistatin 2 and spongistatin 3. A bright colored Southwest Indian Ocean sponge Spirastrella spinispirulifera has also been found to contain related human cancer cell growth inhibitors named spongistatin 4 and spongistatin 6. A method of treating human cancer cells with spongistatin 1, spongistatin 2, spongistatin 3, spongistatin 4 and spongistatin 6 is also disclosed. The approximate mean GI50 of the disclosed compounds in the NCI cell line panel is about 10-10µg/ml.
priorityDate 1993-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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