http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2126200-C
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5052 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
filingDate | 1992-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1998-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a763a89c195799bb14b0d16c62ed8618 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56ba1ffffb428c843e1f898b9fb5db9f |
publicationDate | 1998-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2126200-C |
titleOfInvention | Prolamine coatings for taste-masking orally-administrable medicaments |
abstract | Prolamine fractions of grain proteins, applied in weight ratios of 5 to 100 % re lative to the active agent being coated, effectively prevent the partitioning of water-soluble or water-insoluble drugs a t neutral pH's in the mouth and thereby mask the taste of orally-administered drugs, which normally have a bitter taste, without sacrif icing bioavailability. Zein, gliadin or a mixture thereof, particularly in combination with between 2.5 and 15 % of water-insolubl e vegetable source oil or wax capable of plasticizing the prolamine fraction, when applied to particles, granules, tablet s or other forms of drugs or nutritionals, to an effective thickness of about 1 to about 35 micrometers, in order to encapsulate and preven t release of an orally-administered pharmaceutical or nutritional in a suspension or chewable dosage form until such medicament rea ches the stomach. |
priorityDate | 1991-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.