Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e06d8df5ecb58e082a70a2bd8c474836 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-53 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6813 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
1992-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c24ae2f992ed93a8eaf77c78dbe52986 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5e607246053ffc51241cfe6f0875cc6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79932c610031ecbefb3ed16c9d0cc6ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56958145d9daf9bb47048ee7e48678ed |
publicationDate |
1993-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2119927-A1 |
titleOfInvention |
Duplex-forming polynucleotide conjugates |
abstract |
2119927 9306122 PCTABS00021 The invention provides ligand-binding duplexed structures having significantly enhanced stability under physiological conditions. The structures are provided in the form of polynucleotide conjugates capable of adopting a duplexed structure, in which annealable polynucleotide strands are coupled covalently at one or both ends through a chemical linker which establishes a stabilizing bridge between strands. Various applications for the stabilized duplexed structures are described, including therapeutic applications for example in the treatment of AIDS. |
priorityDate |
1991-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |