| abstract |
The present invention relates to nucleic acid sequences encoding amino acid sequences of the .alpha., .beta., and .gamma. subunits of the high affinity receptor for immunoglobulin E, and for amino acid sequences of the subunits. The invention further relates to a method of producing the receptor by expressing cDNA for its .alpha., .beta., and .gamma. subunits in a host cell simultaneously. Aspects of the invention are methods and compositions to produce the human beta subunit, as well as to inhibit its function, thereby treating or preventing allergic reactions. |