| abstract |
Pharmaceutical formulations for use as immunotherapeutic or prophylactic vaccines comprise a proteinaceous particulate antigen made up of a plurality of self-assembling protein molecules. To enhance the cytotoxic T-lymphocyte (CTL) response, the formulations are adjuvant free. As adjuvant is desirable for enhancing the antibody response, a subject may be administered with two formulations, one with and one without adjuvant. |