| abstract |
Abstract of the disclosure: Substituted benzoylguanidines, process for their preparation, their use as a pharmaceutical or diagnostic, and pharmaceutical containing them. (I) where R(1) to R(3) are H, Hal, (cyclo)alkyl, N3, CN or OH, alkyloxy, phenyl, phenoxy or benzoyl, and their pharmacologically acceptable salts, but with the excep-tion of the compounds benzoylguanidine, 4-chloro-benzoylguanidine, 3,4-dichlorobenzoylguanidine and 3- or 4-methylbenzoylguanidine. They are obtained by reacting a compound II (II) with guanidine, L being a leaving group. |