| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb54e0dd9573d32316a490e981fe014f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
1994-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_678e87664df948eb949211ee7ffce96c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_671079adcca306104f67d5cb429f57c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0991d89fd4c44cd8e156527d0a76bc65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6734024fbf918c0f55647db73d987530
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82815788fb3ffd2c81599cf3a75195ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_342bd42e2a624b288d69368853c51e03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7ebe899af723cdbff4d0fc1d989bfd5 |
| publicationDate |
1994-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2115900-A1 |
| titleOfInvention |
Pharmaceutical screens and antibodies |
| abstract |
Abstract This invention describes a series of assays useful in evaluating the efficacy of agents which inhibit the neurotoxic effects of .beta.-amyloid peptide. These assays employ .beta.-amyloid peptide which is in a predominantly .beta.-sheet conformation. This invention also encompasses antibodies having a specificity for .beta.-amyloid peptide which is predominantly in a .beta.-sheet conformation as well as pharmaceutic formulations containing these antibodies. These antibodies show poor reactivity with .beta.-amyloid peptide which has a great deal of random coil or .alpha.-helix secondary structure. |
| priorityDate |
1993-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |