abstract |
Abstract of the Disclosure Novel piperazine derivatives of formula I: Y-(CmH2m-CHR1)n-CO-(NH-CHR2-CO)x-Z wherein R1, R2, Y, Z, m, n and r are defined as indicated in Claim 1, inhibit the binding of fibrinogen to the fibrinogen receptor and can be used for the treatment of thrombosis, apoplexy, cardiac infarctus, inflammation, arteriosclerosis and tumours. |