http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2111851-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e5edd48190cba3fa70dd3975efd9831 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-135 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-135 |
| filingDate | 1991-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e3b0e333d1266bb09be3ceff2e28717 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b584997f8659df07afeb402c3dbf708a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f769e8a3df3b7429d31ea214e612a0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bc09570572c36b469851028a975e83e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a13d9dad65af0041a690c52710c3305 |
| publicationDate | 1993-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2111851-A1 |
| titleOfInvention | (s)(+)-2-ethoxy-4-[n-{1-(2-piperidino-phenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoic acid |
| abstract | The present application relates to the new (S) (+)-2-ethoxy-4-[N-[1-(2-piperidino-phenyl)-3-methyl-1-butyl]-aminocarbonylmethyl]-benzoic acid and the salts thereof, which have valuable pharmacological properties, namely an effect on the intermediate metabolism, but particularly the effect of lowering blood sugar. The (S)-enantiomer has the general formula: (see formula I) wherein W' represents a carboxy group or an alkoxycarbonyl group having a total of 2 to 5 carbon atoms, wherein the alkyl moiety of the alkoxy group may be substituted by a phenyl group. The invention also relates to the new intermediate products of formulae I, III, IV, and VII and the addition salts thereof. The intermediates are compound of general formulae: (see formula II) (see formulas III,IV, V) A represents a group which can be converted into a carboxy group by hydrolysis, thermolysis or hydrogenolysis, W' represents a carboxy group or an alkoxycarbonyl group having a total of 2 to 5 carbon atoms, wherein the alkyl moiety of the alkoxy group may be substituted by a phenyl group, and W" represents a group which may be converted by oxidation into a carboxy group, and the addition salts thereof. The new compounds can be produced using methods which are known for analogous compounds. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2200588-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9254268-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7915421-B2 |
| priorityDate | 1991-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.