abstract |
3-(6-QUINOLYLMETHYL)-4H-IMIDAZOL-4-ONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY SYNTHELABO An invention of: GĂ©rard CREMER, Jean-Claude MULLER Abstract 3-(6-Quinolylmethyl)-4H-imidazol-4-one deriva-tives corresponding to the formula (I): (I) in which R1 represents an unbranched or branched (C2-C5)alkyl group, R2 and R3 represent, each independently of one another, either a hydrogen atom, or an unbranched or branched (C1-C5)alkyl qroup, or a (CH2)n-aryl group where n = 0 to 3, or R2 and R3 with the imidazole ring can form a spiro-cyclo(C3-C8)alkyl group, as well as their addition salts with pharmaceutically acceptable acids and bases. Therapeutic application. |