| abstract |
Abstract of the Disclosure The invention relates to physiologically tolerated and physiologically degradable polymer-based carbohydrate receptor blockers with an HLB* of 10 to 20 containing: carbohydrate portion - bifunctional spacer - hydrophilic, biodegradable polymer - potentiator, where the carbohydrate portion which is composed of 1 to 20 naturally occurring, identical or different, monosaccharide units is coupled via one or more bifunctional spacers, which is a natural or synthetic molecule, to a hydrophilic, biodegradable polymer, where the polymer in turn is the carrier of one or more spacers, and the hydrophilic, biodegradable polymer is additionally linked to the potentiator which is a crosslinker, one or more groups with hydrophobic, hydrophilic or ionic properties or a solubility improver, to a process for the preparation and to their use in vivo for blocking carbohydrate-recognizing receptors. The carbohydrate receptor blocker causes no intolerance reaction in vivo either in its entirety or in the form of degradation products. |