| abstract |
Stabilized pulverulent active agents, compositions containing them and also a process for obtaining them. Such stabilized active agents enable dry and stable pharmaceutical, dietary, nutritional or cosmetic compositions to be obtained, in which the properties of the said active ingredients are neither modified nor impaired. Such stabilized active ingredients are stabilized by coating with a composition comprising: at least one film forming agent, in proportions of between 2 and 25% by weight of the final mass, selected from polyvinylpyrrolidones (povidone), polyvinyl alcohols, vinylpyrrolidone/vinyl acetate copolymer, vinylpyrrolidone/polyvinyl alcohol copolymer, cellulose derivatives such as cellulose acetate, cellulose acetate phthalate, cellulose butyrate, ethylcellulose and methylcellulose, acrylic and methacrylic polymers and copolymers, and vegetable, animal or synthetic waxes; and, at least one pore-forming agent, in proportions of between 0 and 5%, preferably of between 0.5 and 5%, by weight of the final mass, selected from microcrystalline lactose, low molecular weight polyethylene glycols, calcium carbonate, calcium phosphate, sucrose, sodium chloride and potassium chloride. The stabilized pulverulent active product, in the form of microparticles, possesses a particle size of between 50 and 1000 um, and preferably between 200 and 500 um. |