http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2108282-C

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filingDate 1992-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2003-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e30a5393c1ecbe0273c7682f2ca9dd7
publicationDate 2003-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2108282-C
titleOfInvention Quantitative clotting assay for activated factor vii
abstract An assay for activated factor VII (factor VIIa) has been developed using truncated tissue factor (TF), a soluble mutant form of TF that retains the cofactor function of TF toward factor VIIa Unlike full-length TF, however, tTF appears not to sup-port the conversion of factor VII to VIIa. As a result, the tTF assay for factor VIIa is free from interference from factor VII in the plasma and is therefore specific for factor VIIa. The assay is much simpler than existing assays, because it is a single-stage clot. ting assay performed almost identically to a PT assay. It is also considerably more sensitive than current assays for factor VIIa in plasma. Since he tTF assay is calibrated against a factor VIIa standard, it yields an absolute concentration of factor VIIa in ng/ ml.
priorityDate 1991-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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