| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-61 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2434
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8209
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01031 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82 |
| filingDate |
1992-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85feeebb55063fb12b01583d689b91c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ccb648e228de50d072a9d6380e6b4f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd86ccd1b2e3dcc71b8bcac9d9a61a69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8637eaf30c7ab638150a3db49c3bf52 |
| publicationDate |
1999-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2107916-C |
| titleOfInvention |
Bifunctional genetic markers |
| abstract |
Genetic markers of this invention provide a biochemically assayable reporter activity and a conditionally selectable growth advantage. They comprise a first gene which encodes a product whose activity can be assayed biochemically e.g., .beta.-glucuronidase, to a second gene which confers a conditional growth advantage such as antibiotic resistance in a transformed cell (e.g., neomycin phosphotransferase-II). The marker genes and their translational products are stable in cells. The genetic markers provide for the positive genetic selection and the biochemical and histochemical screening of transformed cells. They can be used as probes for identification and isolation of novel genetic regulatory elements. such as promoters, and the genes they regulate. |
| priorityDate |
1991-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |