| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a95ef521f5f7c989dca4d11435b9ea8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-765
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-2624
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-2609
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-765
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-26 |
| filingDate |
1992-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d0c9d4f466f0a0733f3efe34af995f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e0e7d5d07c65a456bae847a8fe660ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_323f3d9e3c91a88b8bd9f385a6aa7fca |
| publicationDate |
1992-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2106474-A1 |
| titleOfInvention |
Polyoxypropylene/polyoxyethylene copolymers with improved biological activity |
| abstract |
The present invention comprises novel preparations of polyoxypropylene/polyoxyethylene copolymers which retain the therapeutic activity of the commercial preparations, but are substantially free from the undesirable effects which are inherent in the prior art preparations. The preparation entails first condensing propylene oxide to produce a polyoxypropylene polymer and then condensing ethylene oxide with the polyoxypropylene polymer to produce a polyoxypropylene/polyoxyethylene block copolymer of the general formula: HO(C2H4O)b(C3H6O)a(C2H4O)b H wherein a and b are integers. Because the preparations of polyoxypropylene/polyoxyethylene copolymers which comprise the present invention are a less polydisperse population of molecules than the prior art polyoxypropylene/polyoxyethylene copolymers, the biological activity of the copolymers is better defined and more predictable. The polydispersity of the copolymer is very low, average less than 1.07. |
| priorityDate |
1991-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |