Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-13062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-13052 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate |
1991-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2000-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01e6fb4a792bd914af287ced77f8084a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3a9a2949f60864b56051ad4e3b7d33d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b692f5ad2d4d9fb9613b3c3adc9a574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95d811d0c46ba0b694643e91440ec334 |
publicationDate |
2000-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2104396-C |
titleOfInvention |
Viral particles having altered host range |
abstract |
The present application discloses the incorporation of specific membrane-associated proteins into enveloped vector particles to provide an altered host range for these viruses. As a model system, the incorporation of the VSV G protein into Moloney murine leukemia virus (MoMLV)-based retroviral vectors is disclosed. The application discloses methods of introducing genes using modified viruses, and the modified viruse's associated nucleic acid, proteins and cell lines. The methods of introducing genes are disclosed to be useful in a variety of gene therapy methods. |
priorityDate |
1991-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |