| abstract |
ABSTRACT ANTIBIOTIC COMPOUNDS The present invention relates to carbapenems and provides a compound of the formula (I) (I) wherein: R1 is 1-hydroxyethyl, 1-fluoroethyl or hydroxymethyl; R2 is hydrogen or C1-4alkyl; R3 is hydrogen or C1-4alkyl; and the pyridyl group is bonded to the nitrogen of the linking carbamoyl group by a carbon atom in either ring, is substituted with the carboxy group on a carbon atom, in either ring, and is optionally further substituted, on ring carbon atoms, by one or two substituents; or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof. Processes for their preparation, intermediates in their preparation, their use as therapeutic agents and pharmaceutical compositions containing them. |