| abstract |
N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids of formula I wherein R is an aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, araliphatic or heteroarylaliphatic radical having at least 2 carbon atoms, R1 is hydrogen or hydroxy, R2 is an araliphatic or heteroarylaliphatic radical substituted by free or functionally modified carboxy that is bonded directly or by way of a spacer, and R3 is hydrogen, lower alkyl or a group R2, and the salts thereof have valuable nootropic and anti-epileptic properties and can be used in the preparation of a nootropic or anti-epileptic medicament. |