http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2094798-A1

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3d5d6259ad136006dcaf47f794af67aa
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-561
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-544
filingDate 1993-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb744bcb0f9bfb4e40c054da5b11f4d4
publicationDate 1994-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2094798-A1
titleOfInvention Method of mapping polypeptide ligand binding regions
abstract METHOD OF MAPPING POLYPEPTIDE LIGAND BINDING REGIONS ABSTRACT A method is provided for mapping regions of a polypeptide exhibiting selective affinity for a chemical species. The method comprises the steps of digesting the polypeptide with an exoprotease, substantially free of endoprotease activity, to produce a series of partially digested polypeptides of different molecular weight, but a common undigested terminus. The position of the targeted region in the primary structure of the polypeptide is defined by determining the molecular weight of the lowest molecular weight species exhibiting the selective affinity. The method has particular utility for mapping antibody-binding or receptor-binding epitopes.
priorityDate 1992-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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