http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2088162-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94e944e408d7c0eeacfb9df107df5d2f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-59 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-59 |
filingDate | 1991-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6cd78a801aa10c4ecb4825cc7e68a01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6522dedf3926d1d3e490b0439d673121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99ef4af5d00aef120d9a2b32e4298b0c |
publicationDate | 1992-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2088162-A1 |
titleOfInvention | Peptides and pharmaceutical compositions having glycoprotein hormone agonistic or antagonistic activity |
abstract | A peptide having a glycoprotein hormone (ant)agonistic activity, comprising at least 2 partial peptides selected from (1) a partial peptide having an amino acid sequence comprising TDSDS based on the amino acids (92, 88, 89, 90 and 91) of the .beta.-chain of the glycoprotein hormone hFSH or a corresponding sequence of another glycoprotein hormone and/or another animal species, (2) a partial peptide having an amino acid sequence occurring in the .alpha.-chain of glycoprotein hormones and comprising SRAY, (3) a partial peptide having an amino acid sequence comprising TRDL based on the amino acids (34-37) of the .beta.-chain of the glycoprotein hormone hFSH or a corresponding sequence of another glycoprotein hormone and/or another animal species, and (4) a partial peptide having an amino acid sequence comprising AHASTA, derived from the amino acids (82 - 87) of the .alpha.-chain of the human glycoprotein hormones by replacing the cysteines by alanines, or a corresponding sequence of a glycoprotein hormone of another animal species, which partial peptides can be linked together by bridge groups, and variants and derivatives having a glycoprotein hormone agonistic or antagonistic activity. |
priorityDate | 1990-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.