http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2084505-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-59 |
| filingDate | 1991-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f64006e7847ad7036cc59127b11b63f0 |
| publicationDate | 1991-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2084505-A1 |
| titleOfInvention | Substrates and inhibitors for prenyl cysteine methyltransferase enzymes |
| abstract | Compounds of formula (I), in which R1 is alkyl of 1 to 3 carbon atoms; R2 is -COX, wherein X is hydroxy, methyl, amino, thio, H-N-(alkyl of 1 to 3 carbon atoms), N-(alkyl of 1 to 3 carbon atoms)2, or halogen; R3 is a straight or branched chain alkyl of 10 to 25 carbon atoms, or a straight or branched chain alkene including polyunsaturated alkenes of 10 to 25 carbon atoms; and the alkali metal, alkaline earth metal, ammonium, and substituted ammonium salts thereof when R2 is -COOH, are substrates and/or inhibitors specifically for prenyl cysteine methyltransferase enzymes which catalyze the methyl transfer from S-adenosylmethionine to the C-termini of proteins and peptides with prenylated cysteine residues at their C-termini. The compounds, as substrates, are particularly suitable for use in assays for qualitatively or quantitatively detecting the farnesyl cysteine methyltransferase enzymes. |
| priorityDate | 1990-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 184.