| abstract |
Abstract of the disclosure: A novel xanthine derivative of the formula (I): (I) wherein one of R1 and R2 represents substituted or unsubstituted lower alkyl, lower alkenyl, lower alkynyl, substituted or unsubstituted alicyclic alkyl, substituted or unsubstituted phenyl, or substituted or unsubstituted benzyl; and the other represents -(CH2)m-X wherein m is 2 or 3, and X is where a is NH, O or S, and b and d are the same or different and are CH or N or where e, g and h are the same or different and are CH or N; Q represents (wherein R3 and R4 are the same or different and are substituted or unsubstituted alicyclic alkyl), (wherein Y is a single bond or alkylene, n is 0 or 1), (wherein ---- is a single or double bond. Y is the same as defined above), or (wherein Y is the same as defined above); or a pharmacologically accetable salt thereof is disclosed. This derivative has anti-dementia activity. |