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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-102
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70
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filingDate 1992-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce264a95b0b97cd5a4389cf5984d6378
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faf1df12684edcdef8411f90a1d53ad5
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publicationDate 1993-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2081950-A1
titleOfInvention Vaccine for the prevention of infections caused by pasteurella haemolytica
abstract ABSTRACT A vaccine composition for animal administration to elicit an enhanced immune response to challenge by P. haemolytica which produces leukotoxin proteins comprises a synergistic combination of vaccine components: 1. one or more biologically pure antigenic determinants of the leukotoxin protein, the one or more antigenic determinants each comprising an amino acid sequence of at least six amino acid residues selected from an amino acid sequence of Figure 1 and biological equivalents thereof; and 2. a bacterial-free culture supernatant derived from serum-free culture of P. haemolytica. An expression/secretion system for the leukotoxin protein is provided to enhance leukotoxin production.
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priorityDate 1991-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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